Hematopoietic progenitor cell (HPC) transplant continues to be used in more and more situations. In this episode, Dr. Brian Adkins outlines the many issues surrounding transfusion support in HPC transplant patients (yes, including the challenge of ABO-incompatible HPC transplants!).

Dr. Will Flanary is an ophthalmologist and stand-up comic who moonlights as the hilarious “Dr. Glaucomflecken” on social media. The Glaucomflecken videos have earned him an enormous worldwide following, as he has gently parodied physicians of many specialties (including pathology). He and his wife Kristin (aka "Lady Glaucomflecken") join me to share their inspirational story, with NO blood bank learning whatsoever! Even so, you've gotta listen!

Continuing Education episode! Understanding reference lab techniques like adsorption, elution, and enzymes feels like learning a new language! Jan Hamilton is here with an incredible teaching interview to help you learn to speak “reference lab.” This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until June 22, 2025 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! Advances in the practice of Transfusion Medicine happen regularly, and it can be difficult for both learners and those with more experience to keep up with the latest information. Further, many learners (and more “seasoned” types!) lack experience to evaluate strengths and weaknesses of the evidence in the medical literature. Dr. Rich Haspel joins me to describe how to evaluate evidence in the medical literature, and to discuss his take on low-titer group O whole blood. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until May 4, 2025 through Transfusion News Continuing Education on Wiley Health Learning.

CE episode! To celebrate the 100th episode of Blood Bank Guy Essentials, Dr. Chaffin invites multiple previous guests (plus one brand new one!) to share brief "Pearls of Wisdom" with you. Learners of every level are sure to find Transfusion Medicine tips and tools to help care for patients in better ways. Thanks to all who have listened to this podcast in the past 7 years! This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until March 28, 2025 through Transfusion News Continuing Education on Wiley Health Learning.

Rh Immune Globulin prevents at-risk moms from making anti-D, but calculating proper dose can be challenging. In fact, numerous reports have suggested that we mess this up a lot! This episode is a teaching session with me and one of the pathology residents at Loma Linda University, Jessica Hudson. In it, I try to simplify the calculations and discuss some of the mechanics and details around the use of this amazingly effective medication.

Continuing education episode! If a research project has been going on for over 30 years, you would think it's probably pretty good, right? Well, that's how long the REDS research project, sponsored by the US National Heart, Lung, and Blood Institute (NHLBI) has been breaking new ground in Transfusion Medicine. The two co-chairs of the fourth phase, REDS-IV-P, are here to explain why the best is yet to come! This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until July 17, 2024 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! For decades, medical personnel have been aware of the technique of “Acute Normovolemic Hemodilution (ANH),” the collection of blood immediately before surgery followed by infusion near the end. Dr. Steve Frank and his colleagues in the Bloodless Medicine Program at Johns Hopkins believe ANH is an underutilized strategy. He joins the BBGuy Essentials Podcast to share the details of ANH, and show how other facilities can implement ANH as a part of their overall Patient Blood Management Program. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until June 28, 2024 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! Blood shortages happen, but the one associated with COVID-19 is unique (and severe!). AABB Chief Medical Officer Dr. Claudia Cohn explains why and gives practical survival tips. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until March 29, 2024 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! Plasma product names are confusing, but few are as misunderstood as Liquid Plasma. Dr. Chris Gresens explains why LP might be perfect for your transfusion service. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until March 8, 2024 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! When most United States-based healthcare providers think of a hemoglobinopathy, sickle cell disease is the first to come to mind. That is understandable, given how frequently that disease is present in the US. However, worldwide, the various forms of thalassemia are a MASSIVE problem. Dr. Sujit Sheth takes us through the details around this deadly global disease, and how transfusion professionals can aid in care of thalassemia patients. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until March 1, 2024 through Transfusion News Continuing Education on Wiley Health Learning.

Continuing education episode! Usually, red cell alloantibodies are simple (find an antibody, give antigen-negative blood), but occasionally, some of them don't follow the rules! "Antibodies of variable clinical significance" act differently in different patients, sometimes causing hemolysis and sometimes not. They can be very hard to manage, especially because almost all blood donors are incompatible. The Monocyte Monolayer Assay, developed by today's guest, Sandy Nance, and her colleagues at the American Red Cross, helps answer the question, “Do we search the world for rare units of compatible blood, or can we just transfuse ABO-compatible red cells out of our regular inventory?” It's a great story, and this is a rare chance to hear about the MMA from one of the original sources, and to understand how to use it today. This episode is eligible for FREE CME and Continuing Certification credit for physicians and P.A.C.E. contact hours for laboratorians until October 12, 2023 through Transfusion News Continuing Education on Wiley Health Learning.

Platelets have been used to save the lives of patients with low platelet counts for decades. For the most part, they are considered a safe and effective means to correct the problem of a patient not having enough platelets of their own. Despite that, we have wondered for decades about whether or not platelets should be given to patients with certain diseases where their platelets are being removed from circulation, like ITP, TTP, and HIT. My guest in this episode, Dr. Ruchika Goel, looked at platelet transfusion in those three entities, and she has data to share with us that might change the way you transfuse these patients.

In 2017, Dr. Mark Yazer appeared on this podcast to discuss the burgeoning interest in “Low-titer Group O Whole Blood (LTOWB)” for massive transfusions, particularly in trauma settings. Since then, more data and experience are available to guide the use of whole blood for trauma transfusion. Dr. Yazer updates us on the latest whole blood and incompatible plasma transfusion data, and clears up once and for all the "clear fluids" debate! Plus, there's some hockey trash talk...

Despite guidance in a 2015 publication from international experts in immunohematology and transfusion medicine, many clinicians and laboratorians have yet to integrate RHD genotyping into routine practice when a patient’s RhD serologic typing is weaker than expected. In this interview, international immunohematology expert Sue Johnson shows us how we can do better! NOTE: CE credit has expired for this episode.

Transfusion reactions that involve the heart and/or lungs, especially TACO and TRALI, are responsible for more transfusion deaths than any other entity. In this interview, Dr. Cserti-Gazdewich focuses on these two reactions and gives tips and strategies to identify, manage, and prevent them. NOTE: CE credit has expired for this episode.

Warm autoantibodies have a well-deserved reputation as tough challenges, creating unfamiliar situations for both clinical and laboratory staff. I interviewed the authors of two recent papers that outlined best practices in this situation to gain some clarity and help!

Blood transfusion is less likely to transmit infections today than ever. Through a combination of screening questions, donor testing, and direct treatment of blood products, the vast majority of opportunities for transfusion-transmitted infections are eliminated. In this learner-focused interview, Dr. Suchi Pandey from Stanford outlines current strategies to keep blood safe. NOTE: CE credit has expired for this episode.

Every now and then, the routine practice of Blood Banking/Transfusion Medicine gets intimidating. A difficult patient situation arises here, an impossible choice looms there. What do you do when there are no easy answers? Drs Mark Fung and Jay Hudgins are expert Transfusion Medicine practitioners who have years of experience dealing with these “scary” situations! In this special Halloween 2020 episode, they are here to help learners with ideas on how to approach some seemingly impossible situations. NOTE: CE credit has expired for this episode.

Every now and then, when a transfusion service does a pretransfusion workup, they find that the patient's plasma is incompatible with EVERY other red cell! In other words, NOTHING is compatible! These situations are intimidating, and can lead to delays in transfusion. Dr. Jill Storry is an international immunohematology expert, and she shares practical tips for what to do and how to recognize the three main patterns of panagglutinins. NOTE: CE credit has expired for this episode.