Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials. Are there any supplements that can mimic Ozempic? What is amylin and how does it help with weight and sugars? What is this new oral drug "amycretin" in phase 1 trials? and more

Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause. Learn: How it's diagnosed. When and when not to treat. The various treatment. If it is indicated for cardiovascular disease prevention or body composition. Whether or not you should get labs. See more at Dr. Gunter's website

Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide. They also discuss the women's boxing controversy and BMI in athletes.

Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines. Should healthy people even check a vitamin D level? Should they supplement with vitamin D? What people should check or supplement? Click here for the new guidelines

Does semaglutide cause blindness? What is NAION (nonarteritic anterio ischemic optic neuropathy)? What about worsening of diabetic retinopathy with semaglutide? What can you do to minimize the risk of NAION and retinopathy? Get the full study here Read Dr. Brugger's blog

Tirzepatide may be a good option if you have obesity and obstructive sleep apnea. Click here to read the study

Click here to read about the gastric ablation and trial. Click here to see Dr. McGowan's clinic

Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the study

Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues.

Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out.

Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher show

Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his program

Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure study

Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagram

Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/

Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension study

Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines.

Drs. Karl and Spencer discuss whether your doctor needs to look a certain way in order to be a good doctor.

Drs. Karl and Spencer chat with Drs. Jess and Andrea all about popular podcasters like Andrew Huberman etc. and the spread of pseudoscience.

Drs. Karl and Spencer chat about their now defunct supplement company along with the ethics of big pharma direct to consumer marketing (including influencers).