Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Jakob Christensen (Aarhus, Denmark) In this last November episode Bernhard Steinhoff and Jakob Christensen give an update on new data concerning the risk of the offspring of male patients under antiseizure medications. They discuss that the warnings of the EMA about autism spectrum disorders and cognitive impairment that raised major concern now appear less intimidating due to recently published results from a huge Scandinavian registry study.

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Jakob Christensen (Aarhus, Denmark) This week Bernhard Steinhoff talks with Jakob Christensen about the latest news on the risk of antiseizure medications in pregnancy and beyond. They mention new data on teratogenicity and the increased probability of autism spectrum disorders and cognitive impairment of the offspring.

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Kristl Vonck (Gent, Belgium) In this episode, Bernhard Steinhoff speaks with expert Kristl Vonck on the latest advancements in neurostimulation therapies for epilepsy. They explore how innovations in vagus nerve and deep brain stimulation are enhancing personalized treatment approaches, offering new hope for epilepsy patients resistant to traditional therapies.

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Andreas Schulze-Bonhage (Freiburg, Germany) In this episode Bernhard J. Steinhoff and Andreas Schulze-Bonhage discuss the new fascinating perspectives and possibilities of EEG technologies that allow high-class long and ultra-long recordings. Schulze-Bonhage shares these new developments of a method still uniquely important for epileptologists.

Moderator: Theodoros M. Mavridis (Dublin, Ireland) Guest: Messoud Ashina (Glostrup, Denmark) In this episode Theodoros M. Mavridis and Messoud Ashina delve into the findings of the Phase 2 HOPE clinical trial, which assesses the efficacy and safety of Lu AG09222, a monoclonal antibody that targets the PACAP pathway. They explore the potential of this innovative treatment for migraine prevention while highlighting the critical role of the PACAP pathway in migraine pathophysiology.

Moderator: Roland Wiest (Bern, Switzerland) Guest: Randolf Klingebiel (Bielefeld, Germany) In this episode, Roland Wiest and Randolf Klingebiel explore rare causes of myelopathy, a challenging condition due to its infrequent occurrence and diverse origins. They discuss the diagnostic workup, imaging protocols, and differential diagnoses, emphasizing the importance of collaboration between neurologists and neuroradiologists in managing these complex cases.

Moderator: Raphael Wurm (Vienna, Austria) Guest: Majda Thurnher (Vienna, Austria) For this episode, Raphaela Wurm welcomes Majda Thurnher to dive into the challenges and joys of diagnosing spinal cord ischemia as theyexplore MRI protocols, key imaging findings, and the impact of diffusion-weighted imaging.

Moderator: Raphael Wurm (Vienna, Austria) Guest: Dr. Wolfgang Marik (Vienna, Austria) In this episode, Raphael Wurm and Wolfgang Marik explore key neuroimaging techniques for the spine, focusing on when to use CT, MRI, myelography, and spinal arteriography. They discuss how to choose the right technology and address common challenges that can be avoided with proper indications.

EAN moderator: Youssuf Saleh (Oxford, United Kingdom) Guest: Sebastiaan Engelborghs (Brussel, Belgium) In this episode Youssuf Saleh and Sebastiaan Engelborghs discuss dementia prevention, with particular reference to the recently published lancet commission report on dementia prevention, intervention and care. Key areas of discussion include what those risks are, how they can be mitigated and what adaptations the field of neurology and public health need to minimise the burden of dementia in aging populations.

EAN moderator: Marian Galovic (Zurich, Switzerland) Guest: Michel van Putten (Enschede, The Netherlands) In this episode, Marian Galovic talks with Prof. Michel van Putten about the effects of cardiac arrest on the brain. They highlight the role of EEG in assessing long-term prognosis following cardiac arrest and discuss the treatment of rhythmic or periodic EEG patterns.

Moderator: Federica Agosta (Milan, Italy) Guest: Philip van Damme (Leuven, Belgium) In this week’s episodes Federica Agosta hosts Philip van Damme as they discuss the new EAN Guideline on the Management of Amyotrophic Lateral Sclerosis. Find more information here.

EAN moderator: Youssuf Saleh (Oxford, United Kingdom) Guest: Thanh Doan (Trondheim, Norway) For this episodes Youssuf Saleh is joined by Thanh Doan as they discuss the role of brain circuits in neuroscience and how they can be used to advance both our understanding of disease and lay foundations for circuit-based treatments including neuromodulation.

EAN Moderator: Melinda Magyari (Copenhagen, Denmark) Special Moderator: Brett Drummond (Melbourne, Australia) Guest: Susana Otero (Barcelona, Spain) In this episode eanCast: Weekly Neurology is joined by The ECTRIMS Podcast. Hosts Melinda Magyari and Brett Drummond talk about the ECTRIMS-EAN Vaccination Consensus Statement with lead author Susana Otero. Find the full article here.

Moderator: Melinda Magyari (Copenhagen, Denmark) Guest: Celia Oreja-Guevara (Madrid, Spain) In this last August episode Melinda Magyari hosts Celia Oreja-Guevara as they explore the impact of MS on women's fertility, the shift in advice regarding pregnancy, and how pregnancy affects MS activity. They also discuss the importance of consulting a neurologist, considerations for artificial reproduction techniques, and recommendations for disease-modifying therapies, including treating relapses during pregnancy and breastfeeding.

Moderator: Melinda Magyari (Copenhagen, Denmark) Guest: Thomas Berger (Vienna, Austria) Melinda Magyari and her guest Thomas Berger talk about how aging affects MS progression and management, focusing on immunosenescence's impact on the immune response and DMT effectiveness. They cover the rise of comorbidities in older MS patients, the challenges of using DMTs over age 55, the lack of clinical trials for this age group, and share lifestyle tips to improve quality of life and health outcomes.

Moderator: Melinda Magyari (Copenhagen, Denmark) Guest: Nikolaos Grigoriadis (Thessaloniki, Greece) Melinda Magyari hosts Paolo Preziosa as they delve into the significance of central vein sign and chronic active lesions in multiple sclerosis diagnosis and prognosis. They explore how these MRI biomarkers enhance diagnostic accuracy and predict disease progression, emphasizing their potential clinical relevance and the need for further research to optimize MS treatment strategies.

Moderator: Melinda Magyari (Copenhagen, Denmark) Guest: Nikolaos Grigoriadis (Thessaloniki, Greece) Follow Melinda Magyari and her guest Nikolaos Grigoriadis in the first MS episode of this month as they explore the Epstein-Barr Virus and its potential link to multiple sclerosis. They discuss how EBV might trigger or worsen MS, the challenges in confirming this connection, and implications for treatment and prevention. Other MS risk factors, such as genetics, environment, vitamin D levels, and lifestyle, are also covered.

Moderator: Anne Pavy-Le Traon (Toulouse, France) Guests: Giovanna Calandra-Buonaura (Bologna, Italy) and Valeria Iodice (London, United Kingdom) In this week’s podcast episode Anne Pavy-Le Traon hosts two guests, Giovanna Calandra Buonaura and Valeria Iodice, as they discuss a hot topic related to Phenoconversion in Pure Autonomic Failure (PAF). They highlight the natural history of PAF and the importance of recognising this disease as a possible prodromal/ premotor phase of other alpha synucleinopathies. They discuss novel clinical and multimodal biomarkers in early diagnosis of these disorders.

Moderator: Cristian Falup-Pecurariu (Brasov, Romania) Guest: Valentina Leta (Milan, Italy) In this episode, Cristian Falup-Pecurariu discusses with Valentina Leta the relationship between gastrointestinal dysfunction and movement disorders with a focus on Parkinson's disease. They explore the impact of gastrointestinal dysfunction as part of dysautonomia in people with Parkinson's disease, other neurodegenerative diseases, and the importance of identifying and managing these symptoms to improve their quality of life.

Moderator: Cristian Falup-Pecurariu (Brasov, Romania) Guests: Alessandra Fanciulli (Innsbruck, Austria) and Roland Thijs (Heemstede, The Netherlands) In this second episode of July, Cristian Falup-Pecurariu hosts Alessandra Fanciulli and Roland Thijs. They delve into the topic of Cardiovascular Autonomic Dysfunction and cover symptoms, diagnosis, and treatment of conditions like syncope and orthostatic hypotension, emphasizing their significance in neurodegenerative disorders and the importance of distinguishing these autonomic failures in clinical practice.