Sugar, Cancer & The Warburg Effect

Let's discuss more about cancer, sugar and The Warburg effect.

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Link to study & Images: https://youtu.be/I6_QmMuluiE

Show Notes:

0:00 Intro
0:05 Breast, lung, colon, and brain cancer have been linked with deranged cellular metabolism.
0:27 Cancer is the second leading cause of mortality in the US.
1:00 Normal cells aerobically breakdown carbohydrates and fats to create ATP.
1:50 Cancer cells, in the presence of oxygen, ferment glucose to make pyruvate and lactate.
3:10 Mitochondria regulate preprogrammed cell death.
5:10 Dysregulated glucose metabolism fosters a tumor microenvironment that favors expansive growth.
5:35 PET scan is diagnostic imaging tool which uses a radioisotope glucose, fluorodeoxyglucose, that helps to diagnose cancer.
7:00 Metformin, which decreases glucose, is being used in cancer treatment and therapeutics.
9:10 Tumors require a chronic overexpression of lactate. Exercise is a transient acute increase in lactate.
10:04 Lactate can cause a cascade of events which helps the tumor grow more blood vessels.
11:25 By circumventing mitochondria for energy, it’s ability to induce apoptosis is inhibited.
13:00 Your microenvironment can foster or inhibit the growth of a tumor.
14:45 Cold immersion is a mitochondrial therapy.
15:40 There is an association with a lower risk for breast cancer, total cancers and colorectal cancers for people who follow dietary prevention guidelines.