Guest: Mary Beth Pfeiffer With cases being reported in every state and across 80 countries, Lyme disease has become one of the fastest growing vector-borne illnesses in the world. But have you ever wondered how this global health threat came to be? That’s what journalist Mary Beth Pfeiffer investigates in her book, Lyme: The First Epidemic of Climate Change, and with the ReachMD team.

Host: Maurice Pickard, MD Guest: Beth Macy Beth Macy’s Dopesick is a heartbreaking trajectory that illustrates how America’s twenty-plus year struggle with opioid addiction has persisted for this long and has become so firmly entrenched in practically every corner of our country—from desolate cities to once idyllic farm towns. Tune in as Beth Macy joins Dr. Maurice Pickard to illuminate the persistent and often conflicting gaps in the treatment and criminal-justice landscapes while shining a hopeful light on the heroes battling the worst drug epidemic in American history.

Host: Michael Greenberg, MD Guest: Michele Meltzer, MD Rheumatology services are limited or non-existent in many parts of sub-Saharan Africa. Basic diagnostic tests, biological agents, and treatments are either unavailable or not affordable for the majority of people living in that area. This shortage results in patients not having the benefit of early diagnosis and management of relatively cheap and cost-effective therapies. Instead, they present at advanced stages of disease with otherwise preventable morbidity. Host Michael Greenberg chats with Dr. Michele Meltzer, Associate Professor at Jefferson University Hospitals in Philadelphia and President of the non-profit organization, Rheumatology for All, about providing medical training and care for countries with limited or non-existent rheumatology services.

Host: Brian P. McDonough, MD, FAAFP Cigarette smoking is one of the leading cause of preventable death in North America, an unfortunate statistic that is rapidly replicating across the rest of the world. The World Health Organization (WHO) predicts based on current trends that cigarette smoking will kill a billion people this century. But what can be done to reverse this trend? Host Brian McDonough talks with David Sweanor, Adjunct Professor of Law, and Chair of the advisory committee for the Centre for Health Law, Policy and Ethics, at the University of Ottawa. Mr. Sweanor has been spearheading efforts to reduce cigarette smoking nationally and globally.

Host: Matt Birnholz, MD Guest: Luanne Freer, MD Practicing medicine at 17,000 feet brings a unique set of challenges for doctors, including altitude-related sicknesses, IV fluids freezing, and the need for duct tape to serve as an essential medical tool. Dr. Matt Birnholz chats with Dr. Luanne Freer, Founder and Director of Everest ER, a medical clinic at Mount Everest Base Camp serving Everest climbers, support staff, and the local Nepalese population. To find out more information about Everest ER, please visit http://www.everester.org.

Host: Andrew Wilner, MD, FACP, FAAN Guest: Lawrence Loh, MD Almost two-thirds of medical students expect to join a medical mission during medical school and their medical early careers. Yet despite positive intent, such short-term experiences may exacerbate global health inequities and even cause harm. Dr. Lawrence Loh, Adjunct Professor at the University of Toronto Dalla Lana School of Public Health, joins host Dr. Andrew Wilner to talk about the benefits and pitfalls of medical mission work for the communities being served.

Host: John J. Russell, MD Infectious disease has the terrifying power to disrupt everyday life on a global scale, overwhelming public and private resources and bringing trade and transportation to a grinding halt. Host Dr. John Russell sits down with Dr. Osterholm to talk about the book Deadliest Enemy: Our War Against Killer Germs. They talk about how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.

Host: John J. Russell, MD Host Dr. Russell sits down with Dr. Steven Hatch, an infectious disease specialist and author of the book, Inferno: a Doctor's Ebola Story, about his experience in Liberia during the heart of the Ebola crisis. Dr. Steven Hatch first came to Liberia in November 2013, to work at a hospital in Monrovia. Six months later, several of the physicians Dr. Hatch had mentored and served with were dead or barely clinging to life, and Ebola had become a world health emergency. Hundreds of victims perished each week; whole families were destroyed in a matter of days; so many died so quickly that the culturally taboo practice of cremation had to be instituted to dispose of the bodies. With little help from the international community and a population ravaged by disease and fear, the war-torn African nation was simply unprepared to deal with the catastrophe. A physician’s memoir about the ravages of a terrible disease and the small hospital that fought to contain it, Inferno is also an explanation of the science and biology of Ebola: how it is transmitted and spreads with such ferocity. And as Dr. Hatch notes, while Ebola is temporarily under control, it will inevitably re-emerge―as will …

Host: Andrew Wilner, MD, FACP, FAAN Guest: John Kihm, MD Host Dr. Andrew Wilner explores different opportunities to combine medicine with outside interests when off call. Today, he talks with Dr. John Kihm, an internist in private practice in Durham, NC. who fell in love with North Carolina's Outer Banks and Ocracoke Island off Cape Hatteras while a 4th year medical student. He has found a way to combine his passion for volunteer medical work with his passion for flying by commuting to Ocracoke one weekend a month to conduct his special "house call" practice.

Host: John J. Russell, MD Guest: Amy Mackey, MD Hosts Dr. John Russell and Dr. Amy Mackey sit down to reflect on their individual and shared experiences participating in medical missions from their respective vantage points of family medicine and obstetrics & gynecology.

Host: Jennifer Caudle, DO News about the Zika virus have dominated health headlines, but understandings about the full range of viral transmission routes, symptomatology, complications, and rising endemic zones remain unclear for many clinicians. Joining Dr. Jennifer Caudle for updates in recognitions and treatment for Zika virus infection is Dr. Kecia Gaither, practicing OB/GYN and maternal fetal medicine specialist, and perinatal consultant at St. Lukes Hospital in Kansas City, Missouri. Most recently, Dr. Gaither served as Director of Perinatal Outreach at Montefiore Medical Center and Albert Einstein College of Medicine. Prior to this post, she served as the Vice Chairman and Director of Maternal Fetal Medicine in the Department of Obstetrics & Gynecology at Brookdale University Hospital and Medical Center. Dr. Gaither earned her MPH in health policy and management at Columbia University.

Host: John J. Russell, MD A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war.

Host: Alan S. Brown, MD, FACC, FAHA, FNLA Like in the United States, Canadian citizens contend with a high pediatric prevelance of lipid disorders, particularly familial hypercholesterolemia. However, perspectives on clinical care and standards public health priorities to address dyslipidemia differ markedly between these two countries. Can American practitioners and health policy experts alike benefit from Canadian approaches to lipidology? Dr. Alan Brown welcomes Dr. Julie St. Pierre, Professor of Pediatrics at Sherbrooke University in Canada, to discuss pediatric lipid disorder management across North American borders.

Host: John J. Russell, MD In recent years, malaria has emerged as a cause celebre for voguish philanthropists. Bill Gates, Bono, and Laura Bush are only a few of the personalities who have lent their names--and opened their pocketbooks--in hopes of stopping the disease. Still, in a time when every emergent disease inspires waves of panic, why aren't we doing more to tame one of our oldest foes? And how does a pathogen that we've known how to prevent for more than a century still infect 500 million people every year, killing nearly one million of them? In The Fever, journalist Sonia Shah sets out to answer those questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Dr. John Russell hosts this fascinating discussion about her book.

Host: John J. Russell, MD Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. But which one, and how? In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, prizewinning journalist Sonia Shah interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.

Host: Brian P. McDonough, MD, FAAFP Reporting from the Caribbean island of Bonaire, Dr. Brian McDonough provides an update on local public sentiments and concerns around the continuing spread of Zika virus infections across the world.

[Read the Article] To some, end of life care in the United States is considered resource intensive, expensive, and inattentive to patients' needs. So how does the United States compare to other countries? A new study examined several health care measures at the end of life for cancer patients in five European countries, Canada and the United States. Researchers from the University of Pennsylvania Perelman School of Medicine compared the health care experience for cancer patients older than 65, in Canada, Belgium, Germany, England, the Netherlands, Norway and the United States. They examined several clinical measures during the final six months of life. The United States and Netherlands had the lowest percentage of patients dying in the hospital. The United States also had the fewest hospitalizations and the smallest number of days patients spent in the hospital. In contrast, intensive care admissions were twice as common in the United States compared to the other countries. During the last six months of life, patients in Norway and Canada had higher hospital costs than patients in the United States. There was less spending in Germany and Belgium, but the lowest expenditures were in the Netherlands and …

Global health security is the protection of the health of people and societies worldwide. With diseases a plane ride or border crossing away, the importance of global health security has never been clearer. Patterns of global travel and trade pose greater opportunities for infectious diseases to emerge and spread nearly anywhere within 24 hours. The Ebola epidemic in West Africa, which has infected more than 28,000 people across 10 countries and has caused more than 11,200 deaths, highlights the importance of ensuring that every country is prepared to prevent, detect, and respond to outbreaks and emerging health threats. In this session of Public Health Grand Rounds from the CDC, experts discuss how CDC, other U.S. government agencies, and global partners are working to promote global health security as an international priority and accelerate progress toward a world safe and secure from epidemics of infectious disease. For more details on this Grand Rounds session and its participants, click here.

Host: Matt Birnholz, MD Joining host Dr. Matt Birnholz is Sarah Marchal Murray, Chief Operating Officer at The END Fund, a private philanthropic initiative dedicated to controlling and eliminating neglected tropical diseases (NTDs). Over 1.4 billion people globally are affected by one or more of the most common NTDs, including 875 million children. The END Fund focuses on tackling the five most prevalent NTDs: intestinal worms,schistosomiasis,lymphatic filariasis,trachoma, and river blindness.

Guest: Olufunmilayo (Funmi) Olopade, MD, FACP Host: Maurice Pickard, MD Host Dr. Maurice Pickard welcomes Olufunmilayo (Funmi) Olopade, MD, FACP, Walter L. Palmer Distinguished Service Professor of Medicine & Human Genetics, Associate Dean for Global Health, and Director of Center for Clinical Cancer Genetics at the University of Chicago Medicine, Chicago, IL. Dr. Olopade reviews the latest information and best practices in establishing an interdisciplinary program in improving chronic disease treatment worldwide. She reviews challenges and progress toward providing better education, research and training, and service infrastructures addressing global health issues within the United States and around the world.