#63 - Mast Cell Diseases & Systemic Mastocytosis: The Basic Science

The basic science of mast cells is the first episode in our 6-part series exploring Mast cell diseases. To start the series, we explore the intricate workings of mast cells by diving into how they work and what happens when something is off balance.

Have you ever wondered what releases histamine and how this happens? Then this episode is for you!

What we cover in our episode about mast cell disease:

• What are mast cells, and what do they do?

• What are the different types of mast cell diseases?

  • Mastocytosis

  • Mast Cell Activation Syndrome

  • Hereditary Alpha-tryptasemia

• The 7 types of mastocytosis

• The cause of mast cell disease

  • KIT gene mutation in Mastocytosis

More resources about mast cell disease:

• Mast Cell Disease page: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/

• What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/

• What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/

We thank Blueprint Medicines for sponsoring this podcast.